Publications

30. “A unifying paradigm for naphthoquinone-based meroterpenoid (bio)synthesis” Zachary D. Miles,^ Stefan Diethelm,^ Henry P. Pepper,^ David M. Huang, Jonathan H. George,* Bradley S. Moore* Nature Chem. 2017, DOI: 10.1038/NCHEM.2829. (^ contributed equally)

29. Biosynthetically-Inspired Oxidations of Capillobenzopyranol” Henry P. Pepper, Hiu C. Lam, Jonathan H. George* Org. Biomol. Chem. 201715, 4811.

  • Selected as a Hot Article

28. “Biomimetic Total Synthesis of Rhodonoids C and D, and Murrayakonine D” Aaron J. Day,^ Hiu C. Lam,^ Christopher J. Sumby, Jonathan H. George* Org. Lett. 2017, 19, 2463. (^ contributed equally)

27. “Biomimetic Total Synthesis of (±)-VerrubenzospirolactoneHiu C. Lam,^ Henry P. Pepper,^ Christopher J. Sumby, Jonathan H. George* Angew. Chem. Int. Ed. 201756, 8532. (^ contributed equally)

  • Published in a special issue in celebration of the 100th anniversary of the RACI
  • Highlighted as Synfact of the Month in Synfacts
  • Highlighted in Chemistry in Australia

26. “Biomimetic Total Synthesis of Hyperjapones A-E and Hyperjaponols A and C” Hiu C. Lam, Justin T. J. Spence, Jonathan H. George* Angew. Chem. Int. Ed. 2016, 55, 10368.

  • Selected as a Very Important Paper
  • Highlighted in Synfacts
  • Highlighted in Chemistry in Australia

25. “A Biomimetic Synthetic Approach to the Frondosins” Kevin K. W. Kuan, Aylin Hirschvogel, Jonathan H. George* Aust. J. Chem. 2016, 69, 1420.

  • Invited contribution to the RACI Research Awards Special Issue

24. “A mechanistic study on the inhibition of α-chymotrypsin by a macrocyclic peptidomimetic aldehyde” Xiaozhou Zhang, John B. Bruning, Jonathan H. George, Andrew D. Abell* Org. Biomol. Chem. 2016, 14, 6970.

23. “Some Chemical Speculation on the Biosynthesis of Corallidictyals A-D” Adrian W. Markwell-Heys, Jonathan H. George* Org. Biomol. Chem. 2016, 14, 5546.

  • Invited contribution to the 2016 New Talent Special Issue
  • Highlighted in Hot off the Press in Natural Product Reports

22. “Total Synthesis of Peniphenones A-D via Biomimetic Reactions of a Common o-Quinone Methide Intermediate” Justin T. J. Spence, Jonathan H. George* Org. Lett. 2015, 17, 5970.

21. “Some reactions of azides with diynyl-bis(phosphine)ruthenium-cyclopentadienyl complexes” Michael I. Bruce,* Alexandre Burgen, Jonathan H. George, Brian K. Nicholson, Christian R. Parker, Brian W. Skelton, Nancy Scoleri, Christopher J. Sumby, Natasha N. Zaitseva J. Organomet. Chem. 2015, 797, 185.

20. “The Biosynthesis and Biomimetic Synthesis of Merochlorins A and B” Henry P. Pepper, Jonathan H. George* Synlett 2015, 26, 2485.

  • Invited Synpacts article

19. “Total Synthesis and Structure Revision of (-)-Siphonodictyal B and its Biomimetic Conversion into (+)-Liphagal” Adrian W. Markwell-Heys, Kevin K. W. Kuan, Jonathan H. George* Org. Lett. 2015, 17, 4228.

18. “Biomimetic Total Synthesis of (±)-Yezo’otogirin A” Hiu C. Lam, Kevin K. W. Kuan, Jonathan H. George* Org. Biomol. Chem. 2014, 12, 2519.

  • Selected as a Hot Article

17. “Biomimetic Total Synthesis of (±)-Doitunggarcinone and (+)-Garcibracteatone” Henry P. Pepper, Stephen J. Tulip, Yuji Nakano, Jonathan H. George* J. Org. Chem. 2014, 79, 2564.

16. “Selective aliphatic carbon-hydrogen bond activation of protected alcohol substrates by cytochrome P450 enzymes” Stephen G. Bell,* Justin T. J. Spence, Shenglan Liu, Jonathan H. George, Luet-Lok Wong Org. Biomol. Chem. 2014, 12, 2479.

15. “Biomimetic Total Synthesis of (±)-Merochlorin A” Henry P. Pepper, Jonathan H. George* Angew. Chem. Int. Ed. 2013, 52, 12170.

  • Selected as a Hot Paper
  • Highlighted as Synfact of the Month in Synfacts
  • Highlighted in Chemistry in Australia

14. “Biomimetic Total Synthesis of ent-Penilactone A and Penilactone B” Justin T. J. Spence, Jonathan H. George* Org. Lett. 2013, 15, 3891.

13. “Biomimetic Total Synthesis of (±)-Garcibracteatone” Henry P. Pepper, Hiu C. Lam, Witold M. Bloch, Jonathan H. George* Org. Lett. 2012, 14, 5162.

  • Highlighted as Synfact of the Month in Synfacts
  • Highlighted in an ACS Virtual Issue on Natural Product Total Synthesis

12. “Total Synthesis of (+)-Aureol” Kevin K. W. Kuan, Henry P. Pepper, Witold M. Bloch, Jonathan H. George* Org. Lett. 2012, 14, 4710.

  • Most read Organic Letters article in September 2012
  • In the top 5 most read Organic Letters articles for 2012

11. “Synthesis of a Liphagal-Frondosin C Hybrid and Speculation on the Biosynthesis of the Frondosins” Henry P. Pepper, Kevin K. W. Kuan, Jonathan H. George* Org. Lett. 2012, 14, 1524.

10. “Structural Reassignment of Cytosporolides A-C via Biomimetic Synthetic Studies and Reinterpretation of NMR Data” Justin T. J. Spence, Jonathan H. George* Org. Lett. 2011, 13, 5318.

  • Highlighted in Hot off the Press in Natural Product Reports

9. “Biomimetic Synthesis of Polycyclic Polyprenylated Acylphloroglucinol Natural Products Isolated from Hypericum papuanum” Jonathan H. George,* Micha D. Hesse, Jack E. Baldwin, Robert M. Adlington Org. Lett. 2010, 12, 3532.

8. “Enantiospecific, Biosynthetically Inspired Formal Total Synthesis of (+)-Liphagal” Jonathan H. George,* Jack E. Baldwin, Robert M. Adlington Org. Lett. 2010, 12, 2394.

7. “Biomimetic rearrangements of simplified labdane diterpenoids” Jonathan H. George, Mark McArdle, Jack E. Baldwin, Robert M. Adlington* Tetrahedron 2010, 66, 6321.

6. “Total synthesis of (+)-A83586C, (+)-kettapeptin and (+)-azinothricin: Powerful new inhibitors of the beta-catenin/TCF4 and E2F-mediated gene transcription” Karl J. Hale,* Soraya Manaviazar, Jonathan H. George Chem. Commun. 2010, 46, 4021.

5. “Synthesis of A83586C Analogs with Potent Anticancer and beta-Catenin/TCF4/Osteopontin Inhibitory Effects and Insights Into How A83586C Modulates E2Fs and pRb” Karl J. Hale,* Soraya Manaviazar, Linos Lazarides, Jonathan H. George, Mohamed El-Tanani et al. Org. Lett. 2009, 11, 737.

4. “Total Synthesis of (+)-Azinothricin and (+)-Kettapeptin” Karl J. Hale,* Soraya Manaviazar, Jonathan H. George, Marcus A. Walters, Stephen M. Dalby Org. Lett. 2009, 11, 733.

3. “A Synthetic Approach to the Communesins” Jonathan H. George, Robert M. Adlington* Synlett 2008, 16, 2093.

2. “Mechanistic Studies on the O-Directed Free Radical Hydrostannation of Disubstituted Acetylenes with Ph3SnH and Et3B and on the Iodination of Allylically Oxygenated alpha-Triphenylstannylalkenes” Paschalis Dimopoulos, Jonathan H. George, Derek A. Tocher, Soraya Manaviazar, Karl J. Hale* Org. Lett. 2005, 7, 5377.

1. “O-Directed Free Radical Hydrostannations of Propargyl Ethers, Acetals, and Alcohols with Ph3SnH and Et3B” Paschalis Dimopoulos, Audrey Athlan, Soraya Manaviazar, Jonathan H. George, Marcus A. Walters, Linos Lazarides, Abil E. Aliev, Karl J. Hale* Org. Lett. 2005, 7, 5369.